Friday, July 26, 2013

As the government continues to shut down family farms, your ability to make good food choices diminishes

Friday, July 26, 2013 by: Jonathan Benson, staff writer
Tags: Big Ag, small farms, federal government

Learn more: http://www.naturalnews.com/041359_Big_Ag_small_farms_federal_government.html#ixzz2aCgP3gXb(NaturalNews) Though much of it flies under the mainstream radar, there is a coordinated effort afoot to completely stamp out all private, small-scale food production in the United States, which means your ability to access the clean, high-quality foods of your choice is rapidly diminishing. In his new book Life, Liberty, and the Pursuit of Food Rights, investigative journalist David E. Gumpert covers this pertinent issue in depth, highlighting the ongoing string of government raids and other oppressive tactics regulators are taking to eliminate your freedom of food choice.

In a chapter entitled Is There Such a Thing as Private Food?, Gumpert paints a grim picture of what America's harsh regulatory climate has and is doing to family farmers. What used to be a free and open system of private food production and distribution has devolved into a type of corporate food monopoly controlled by the U.S. Department of Agriculture (USDA), the U.S. Food and Drug Administration (FDA), and various other nanny state food agencies that have assumed authority over what people can eat.

Many of the cases outlined in this particular chapter have previously been covered here at NaturalNews -- the shutdown of Amish raw milk farmer Daniel Allgyer's Pennsylvania farm; the armed SWAT raid of the Manna Storehouse in Ohio; and the forced closure of the private Underground Market in San Francisco are just a few prominent examples. But each of these independent events represents just a small piece of a much bigger agenda to eliminate the fundamental right to choose one's own food.

"In the public system's expansion, farming has become increasingly removed from the output process of the nation's food," writes Gumpert in his book about the growing disconnect between people and the foods they eat. "More and more of the nation's farms have become essentially subcontractors to huge corporations that dictate the feed, breed, housing, and life span for chickens, pigs, and cattle."

Big Ag corporations using power of state to drive private food production into extinction

This, of course, has been the goal of Big Ag all along -- to buy up or put out of business all American farms that refuse to meld their production outputs into the larger public food system. Those that try to operate outside the system with private food buying clubs, non-inspected goods distribution systems, and other decentralized models eventually become the target of the state, which increasingly exercises the heavy hand of tyranny to force compliance.

For Daniel Allgyer, this meant facing armed FDA agents who showed up at his private farm one morning to conduct an illegal inspection, which eventually resulted in the shutting down of his farm. For the Stowers family of Manna Storehouse, it meant being terrorized by a SWAT team that held the family hostage while stealing their private files and other documents. And for Quail Hollow Farm in Nevada, it meant being ordered to throw away hundreds of pounds of farm-fresh food.

Even bake sales, lemonade stands, and other neighborhood-based food events have come under increased regulatory scrutiny in recent years, which in 2011 prompted the formation of an inaugural "Lemonade Freedom Day" protest to assert the right of Americans to freely choose their own food without having to first get permission from Big Brother.

"In the recent past, bureaucrats and law enforcers have shut down lemonade stands for not having permits or licenses," wrote the event's organizers on their website, echoing the sentiment of many others who have been targeted using similar tactics.

Be sure to read the full published excerpt from Gumpert's book here:
http://foodfreedomgroup.com

You can also check out his book to learn more about the ongoing war against food freedom in America today:
http://www.publishersweekly.com

Sources for this article include:

http://foodfreedomgroup.com

http://www.truth-out.org

http://www.publishersweekly.com

Earth Chakras: The 7 Key Energy Vortices of Mother Earth


July 25, 2013 | By | 2 Replies
WIKI -= Ayers Rock1
Ayers Rock, Australia
Christina Sarich, Staff
Waking Times 
Just as the physical body has seven (or more) identifiable energy centers, or swirling vortices of subtle energy, so does the planet have chakra centers that govern her health and act as a reflection of her energetic evolution. Dr. Hiroshimi Motoyama developed a way to measure the chakras of the human body – to give them a scientific basis, when they were considered purely metaphysical for centuries, though saints, sages, monks and yogis knew of their existence long before they were recognized by scientific instruments.
There are many cultures that conceive of an energetic system which runs the body, but the Yogic Chakra System is said to be 4000-5000 years old. Chakra translates loosely to mean ‘wheel’ from Sanskrit, but it more accurately describes a vortex of rotating energy. Some chakra systems contain twelve primary chakras, others fewer, but they refer to a map of the energy circulating through the body, primarily through the spinal column. Each chakra is situated near an endocrine gland that is responsible for regulating hormonal reactions in the body. The chakras also act as translators of energy. They assimilate energy from surrounding influences, including your own emotions and thoughts and the chakras of others. In the yogic conceptualization of the chakra system there are seven primary energy chakras.” (Yogaforums.com)
Each chakra has its own bandwidth of energy, and it governs the perspective of each person at that vibration. The earth’s chakras are very similar. They are reflective of the root all the way to the crown. The Chinese/Japanese conceptualization of the chakras or meridians, is slightly different than the Indian conceptualization as is the Kabbalistic, but they weave into a very cohesive understanding of the energy body.
Such is also the case with the earth’s energetic vortices or chakras. “The Earth is a living being, with its own creative, evolutionary will, and with its own methods for enacting that purpose. If we look at nature, we discover that design and innovation – the architect and the inventor – are at work. What is the goal of this effort? Alone, among the planets in the solar system, Earth is the matrix for life. What are the maximum potentialities for life? It is the true will of the Earth to find the answers to this question, and to communicate these results to other laboratories of life throughout the universe.” (earthchakras.org)
The same way that kundalini energy weaves its way up the spine from the root of the spinal chord in a human being, in a DNA-like fashion, energy also rotates throughout the planet.
Here are the most commonly accepted geographic locations of the planet’s chakra system and what they represent spiritually. (It is thought that the chakras can shift locations based on planetary cycles):
1st Chakra – Corresponds to the Root or Mooladhara Chakra Mt. Shasta in California is considered the root chakra of the planet. (Some also say this is the 5th chakra of the planet.) This energy center is considered primal and ‘base.’ Here is where the universal life force is considered to gather before it becomes life – and is representative of the geysers which rush to the surface with energy the same way that kundalini energy is thought to rush to the crown or pineal gland was awakened from the root chakra.
2nd Chakra – Corresponds to the Sexual Chakra or Swadhistana Lake Titicaca Peru/Bolivia is considered the 2nd chakra of the planet. The Plumed Serpent – found in many South American myths is representative of the kundalini energy rising to the sexual chakra of the planet. Also called the rainbow serpent, this center has some of the most ley crossroads or ley lines on the planet, second only to Bali. It is where our primal energy starts to ‘birth’ itself, quite literally into form. Some say that it is through this chakra that the earth overcomes entropy.
3rd Chakra – Corresponds to Manipura or the Solar Plexus Chakra Uluru, otherwise known as Ayers rock in Australia along with Kata Tjuta are the home of the earth’s 3rd chakra. This huge, monolithic rock is in the Northern Territory of Australia. This is where dreamtime legends arise from the Aboriginal people’s. Anangu life revolves around the Tjukurpa (sometimes wrongly referred to as the Dreamtime). To the Aboriginal people, this is the ancestral period of when the world was being formed. Kata Tjuta is considered Uluru’s sister rock formation. In us, the solar plexus is where we digest emotion – on the planet, it is where we will one day realize a legend told by the Aborigines from the ‘umbilical chord’ of the planet.
4th Chakra – the Heart Chakra, called Anahata in Indian traditions Glastonbury, Somerset and Shaftesbury, Dorset comprise the center of the world’s heart chakra. This is the home of the holy grail. It is perhaps, also our greatest contribution to the ourselves, and our fellow sentient beings on this planet -  to open our hearts to heal the earth and allow her to embody her rightful place as a peaceful, loving satellite in space. Interestingly, this is an area known for high levels of crop-circle sightings that exhibit magnetic abnormalities.
5th Chakra – the Throat or Vissuddha Chakra The throat or voice of the planet is the located near the Great Pyramids near Mt. Sanai and Mt. Olives in the Middle East. This is the one chakra that does not exist at a ley line. It is the exact center of the earth’s land mass as it currently is configured. Modern day turmoil in the Middle East is considered to be ‘the cries of the mother’ or the voice of the planet calling for help.
6th Chakra – The Pineal Glnd or Third Eye Chakra This chakra can shift – it is called the Aeon activation Center. Now it is considered to be in Western Europe but will likely move over the next several thousand years. This chakra is the one that opens portals and allows extra-dimensional energy to enter this world. Just like our pineal gland allows us to recognize other dimensions and realities, so does the 6th chakra of the earth.
7th Chakra – the Crown Chakra or Sahasrara, the Thousand Petaled Lotus, the Highest Energy Center Mt. Kailas in the Himalayas in Tibet is considered the ‘roof of the world’ and also our earth’s crown chakra. The highly develop consciousness of Tibetan people, as evidenced through the Dalai Lama’s teachings is indicative of the energy that resides at the crown chakra of the planet. Just as our own crown connects our will with Divine will, so does Mt. Kailas connect the planet with her spiritual destiny.
The following video features moving imagery from these 7 sacred sites:


About the Author
Christina Sarich is a musician, yogi, humanitarian and freelance writer who channels many hours of studying Lao TzuParamahansa YoganandaRob Brezny,  Miles Davis, and Tom Robbins into interesting tidbits to help you Wake up Your Sleepy Little Head, and See the Big Picture. Her blog is Yoga for the New World. Her latest book is Pharma Sutra: Healing the Body And Mind Through the Art of Yoga.

This article is offered under Creative Commons license. It’s okay to republish it anywhere as long as attribution bio is included and all links remain intact.

Meditation and “Drugs” like Cannabis!

Meditation and “Drugs”

July 26, 2013 | By | Reply
Flickr-bubbles-Beatnik Photos
Jay Michaelson, Reality Sandwich
Waking Times
It’s a not-so-dirty little secret that most of today’s leading meditation teachers were interested in drugs. By “drugs,” of course, I don’t mean alcohol or Oxycontin, but rather that subset of chemicals which our society has deemed unfit for human consumption, including cannabis, psilocybin, MDMA, and others. Many of today’s leading Buddhist teachers, for example, credit their first taste of altered mind states not to samadhi but to LSD or mushrooms, and almost every spiritual teacher I know (and I know a bunch) smoked pot. Some still do.

So what’s the connection? Why do people who like drugs (I’ll stop scarequoting the word, even though I shouldn’t) like meditation? And what’s the relationship between them?

1. Pleasure

The first and simplest answer is that both drugs and meditation are pleasurable – and a specific kind of pleasure, namely pleasures of the mind. Of course, on the surface of things, meditation and psychedelics seem to be quite different: one is boring and calm, the other wild and crazy. Yet, as entheogen users and yogis know, neither image is accurate. While some chemicals do indeed lead to ecstasy and blurring of boundaries, others lead to their sharpening, and to quiet states of reflection. And while meditation does generally cause calm to arise in the mind, it also leads to ecstasy, delight, religious/spiritual feelings, and rapture — particularly when the faculties of concentration are heightened.
I remember, when I had just started meditating, it was like I had received the answer key to a hundred spiritual questions. “Aha! This is what they were talking about when they said that God is everywhere!” The attention brought to mundane objects renders them everyday miracles, and an opened heart makes davvening a cathartic, healing experience. Suddenly simple phrases that seemed like clichés — “Be Here Now” — became full not only of truth, but of invitation. They cease to sound like pop psychology (“Remember, bourgeois busy people, if you just become ‘present’ you can do all sorts of things and be a more successful businessman/lover/person.”) and instead sound like a call to home, to the One.
And, of course, meditation offers these benefits without the side effects of chemicals, and with longer duration. To be sure, the buzz of concentration is also temporary — but with practice, it can arise on and off for days, rather than for a few hours. It takes much more work, but the pleasure it brings is, after all, only a side-effect of an overall process which greatly increases mental acuity. That is, it’s really good for you. Perhaps this is why many (though not all) of us relinquish plant medicines and chemical entheogens once we take up meditation in earnest.

The type of pleasure is similar as well. When you’re stoned, or rolling, or tripping, certain sensual sensations get enhanced. You can see and feel music when you’re on ecstasy. The taste of some kinds of food on marijuana is, as a stoner would say, “intense.” Everybody knows this, and it’s why many people use drugs. (Of course, many people smoke pot just to get wasted, not to have heightened visual, tactile, or other sensual experiences. But they are not my subject here.) These substances are not an escape from reality, but a magnifying glass held up to it. Intimate details of how the mind works, of how fabric feels, of music. Drugs can make every potato chip a delicate, crispy, greasy delight.

Meditation is about the same process of ‘intensifying’ daily experience, not by pursuing ever-more visceral thrills, but by quieting the mind enough to — in the words of Warren Zevon — “appreciate every sandwich.” (Zevon coined that phrase when David Letterman asked him what effect his diagnosis of terminal illness had on his day-to-day life.) I used to see a contradiction between the ethos of “seizing the day,” living as fully as possible, and the contemplative life, which I associated with a withdrawal from much of human experience. Eventually, though, I came to understand that a contemplative path is the logical extension of living deliberately. There are, really, only two choices available to someone who wants to suck the marrow out of life: either continually seeking more extreme experiences, or making every experience ‘extreme.’ Some people can apparently do the former, but I find that tiring. Meditation allows me to “suck the marrow” out of each tree, table, soda, or breath. By eliminating signal noise and stopping thought, the true colors of the phenomenal universe become revealed, in ever-increasing brilliance. It’s not like being stoned all the time, because there is not the disorientation and tripping up of the rational mind that occurs on pot. But it’s like being stoned in the sense of tastes, touches, smells, sounds, and sights all becoming enhanced, kinesthetically interchanged, and — simply in their non-conceptual presence — enough reason to live.

Incidentally, I was surprised, when I started meditating, that so much pleasure would result. Of course, people who meditate often talk about rapturous union with Being, or dissolution in the Divine, and these do sound very pleasant indeed. But I still didn’t expect it, as if anything “spiritual” had to be austere, or subtle, or boring. Was I wrong! Apart from all the deeper benefits of meditation, the sheer volume of joy is astonishing. In my experience, it beats any other high.

2. Altered Mind States

A second point of similarity between drug use and meditation is that both lead to states of consciousness that are different from the ordinary. Enjoying these seems to be a matter of taste. A lot of people like to take vacations in foreign countries. Some like exotic foods. And many others like vacations from their ordinary modes of consciousness into a different ‘mind-space’ where new insights can occur and even ordinary stimuli (and even without the sensual enhancement above) can be experienced in a whole new way.

Many people deeply fear altered states of consciousness, I think because they are overly afraid of their own non-rational minds. Subscribing to a worldview in which ‘rational’ rules of decency, propriety, etc., govern every aspect of life means relying on our capacities of rational judgment for every important decision. And so, mind-states which relegate such faculties to a subordinate or even invisible role is scary. Now, of course, I’m all for rational judgment making most decisions in the world, and certainly all of those which seriously affect other people. But is it a rational judgment to dance? To let go of the self in orgasm? To fall in love? Some of our most transcendent moments come when the rational mind is quieted and something else takes its place. In some aspects of life, being in touch with the nonrational is essential to being human.
Purely for humanistic reasons, then, I think that altered mindstates are an essential condition of living a full life. Of course, one can do without them, just as one can do without art, dance, sex, and other Divine gifts. But I think it’s a shame to do so. I think something is missing, something impoverished, when they are lacking.

3. Truth

But, of course, many entheogen users and nearly all meditators want to make a further claim: that these particular altered mindstates lead to truth. This isn’t just about getting high and having fun, they say; this is about knowing deeply the truth of your own experience, or even of the fundamental nature of existence itself. Just sit and watch your breath, some Buddhists say, and eventually you’ll intuitively understand the four noble truths, the basic facts of life.

And indeed, this has been my experience. Fortunately, I have been able to set aside large swaths of time to practice, and I have come to such intuitive understandings along the Theravadan Buddhist path, in particular on a five-month silent retreat I completed in February, 2009. I’ve then re-examined and re-evaluated those insights off-retreat – and they’ve tended to hold. The distractions (I should start a publishing house!) have not passed the test of time, but the deep stuff, e.g. about suffering being an inevitable consequence of clinging — that stuff has stuck, and it seems true to me.

That said, when it comes to claims of “truth,” things do get tricky, because there is some information that entheogens reveal which meditation rarely reveals, and some information which meditation reveals that drugs and chemicals don’t. For example, it takes huge amounts of concentration over long periods of time to enter one of the meditative absorptions (jhanas) which resemble, in some ways, distinct “realms” apart from this one, and even the most intense which I have seen described (and, a fortiori, which I have experienced) do not compare to the experiences of journeys on ayahuasca or other plant medicines. I’m not aware of a way to experience those phenomena without the medicine.

And, at the same time, while ayahuasca journeys yield a wealth of information about other realms and one’s own heart, they tend not to offer the level of analytical distinction that accompanies meditative insight. That arises in meditation (and in many other ways, of course).

To me, the resolution of this tension is obvious: plant medicines are good for some kinds of knowledge, and meditation for others. But, spiritual people being the way we are, there’s often a lot of heat (and only some light) on these points, with some people insisting this kind of knowledge is good but inferior, and others countering that, no, that kind of knowledge is the preliminary one and this is ultimate, and so on. This is particularly the case because we all carry baggage related to spiritual practice. Many meditators had early, naive, and unpleasant experiences with drugs, and so assume that even the most rarified of ibogaine journeys is nothing more than their lousy acid trip at a Dead concert in the 70s. Conversely, many users of plant medicines have never had the opportunity to meditate in a conducive setting – e.g., a silent retreat of five days or more — and so assume that either they can’t meditate, or meditation is all a dry slog.

Personally, however, I’ve found that the two paths enrich each other. Most of my work with medicines is, I think, behind me at this point in my life. Yet when I was more involved with them, I found that the ability to stabilize, to tease apart the strands of a mind-made story, and to be a little dubious of what seems to be true to the mind, all served me very well in my own shamanic work. And I have found that the intensity of entheogenic work has been able to push my cognitive reset button when more gradual practices such as mindfulness have been ineffective, or too difficult. At present, my vipassana side is winning out over my shamanic side, and I tend to prefer clear insight over mind-states and multi-realm experiences which seem susceptible to misinterpretation. But, you know, go tell that to Ayaruna.

All that said, I am not a spiritual supercessionist. There are many in the spiritual world who, having taken up yoga or meditation, regard drugs as a useful preliminary, a glimpse of the orchard perhaps, but ultimately something to be gotten beyond. My own path does reflect this somewhat, but I have also met responsible plant aficionados who continue to deepen their practice with medicines. To each their own.
I’m not entirely pluralistic, though. As I’ve written before in these pages, I would say to my fellow Sandwichers that, in my humble opinion, a meditation practice is a necessary prerequisite for any work in shamanic realms, with energy, or with the supernatural in any form. I think having out-of-body experiences with possibly-alien intelligences without having a meditation practice is like flying an airplane without basic aviation training or navigational instruments. Just seeing, over and over again, that the illusions of consciousness do not constitute a “self” is worth the price of admission. So is just seeing, over and over again, that you can have a certain experience and still be wrong about its nature. But more than that, I think the mind-sharpening practices of meditation provide balance and focus in any entheogenic or other-worldly work. At the very least, it’s the warm-up exercise.


It’s a neat little twist: visions brought on by drugs and plant medicines invite people to meditation, and then meditation becomes the necessary preliminary for deeper practice with drugs or other modalities. One path shows you other realms, the other teaches you how to navigate them – and this one as well. Ultimately, all of us learn, usually the hard way, that the exciting bells and whistles of spiritual experience all pass away, and indeed, that the more light one invites into one’s life, the more shadow one invites as well. For this reason, more cool experiences – including powerfully transformative ones – tend to lose their appeal as aids to spiritual progress. They’re still a great way to spend one’s time, but they aren’t more than that. They aren’t “it.” Nothing, of course, is “it”; just the slipperiness with which one navigates the its and yous of life in this realm, hopefully making things a little happier for the rest of us along the way.

Thursday, July 25, 2013

Size Matters: Are Nano-Particles Found In Common Processed Foods Safe for Consumption?

July 25, 2013 | By  
Powdered Donut
Image Source
Jill Richardson, Guest
Waking Times
Even food manufacturers often don’t know if nanoparticles are in the food they sell and no one knows if they’re safe to eat.
They’re found in M&Ms, Dunkin’ Donuts, Jell-O pudding, and even Pop-Tarts. Scientists don’t know if they’re safe to eat. The government doesn’t regulate these things. Even food manufacturers often don’t know this technology is in the food they sell. You probably don’t either.I’m talking about nanoparticles.
Nanoparticles are particles so tiny they must be measured in nanometers — one billionth of a meter. If a nanoparticle were the size of a football, then a red blood cell would be the size of the field. They’re at the heart of a new $20 billion business.
The most important thing to know about this emerging technology is that size matters. Common materials like silver or titanium dioxide take on new properties when they’re shrunk to tiny proportions.
Silver in nano form becomes powerfully antimicrobial. Companies are already taking advantage of this by selling nanosilver-impregnated socks that won’t stink.
Non-stinky socks certainly sound nice. But is nanosilver safe? Silver is a common, safe metal, but nanoparticles are small enough that they can go places that larger molecules can’t. For example, they can cross the blood-brain barrier. Just because a chemical is safe, that doesn’t mean it’s safe in a teensy, nano form.
Early research into commonly used nanoparticles, like silver and titanium dioxide, raises concerns. The group As You Sow points out that nanoparticles can penetrate cells and interfere with cellular functions. And yet, the National Nanotechnology Initiative spent more than 16 times more on product development than on safety testing in the last three years.
So how about those nanoparticles in your food?
Titanium dioxide is a common food additive used as a white pigment. A 2012 study tested common foods to find whether the titanium dioxide used was nano or not. They found them in M&M’s, Betty Crocker Whipped Cream Frosting, Jell-O Banana Cream Pudding, Mentos, Trident and Dentyne gums, Vanilla Milkshake Pop-Tarts, and Nestlé Original Coffee Creamer.
As You Sow followed up by testing powdered sugar coated doughnuts from Dunkin’ Donuts and Hostess. Both had nano-sized titanium dioxide. This raises another question: Why do food manufacturers need to put a white pigment in powdered sugar? Isn’t it already white?
Here’s the point: Nanotechnology is here, and it’s already in our food.
And, unfortunately, nobody’s really on top of this newfangled stuff. Even though size matters in the real world, it doesn’t matter in our regulations. If a chemical is legal in food, then it’s legal in nano form. No labels needed!
Consumers already get tons of info about nutrition, trans fats, and allergens. We need to know what’s in our food, so our government makes companies tell us. But in the case of nanoparticles, sometimes food manufacturers don’t even know themselves when nano is in their products because it was placed in there by one of their suppliers.
Even when nanoparticles aren’t in what we eat, could they seep in from food packaging? Do the nanoparticles migrate from the packaging into the food? Nobody knows yet.
It’s all just one grand experiment, and we’re the guinea pigs.
If you want to avoid nanotechnology in your own body — at least until they’re proven safe for human consumption — your best bets are to buy organic food and avoid processed foods.
Even if they’re proven safe later on, it will be worth the effort. When you load up on fresh fruits and vegetables and skip the doughnuts and candy, you do your health a favor.
But for our society as a whole, leaving this up to individual responsibility is unacceptable, especially when consumers can’t even see these tiny particles to know which foods to avoid. An easy first step is labeling foods containing nanoparticles. Better yet, companies should not be allowed to put them in our food until they’re proven safe.
The federal government is holding a meeting this September to discuss the potential risks of nanotechnology and how to manage them. Until adequate safety testing is completed, let’s get nanoparticles out of our food.
About the Author
Jill Richardson is a columnist for OtherWords, and is also the author of Recipe for America: Why Our Food System Is Broken and What We Can Do to Fix It.

Cannabinoids Elicit Antidepressant-Like Behavior And Activate Serotonergic Neurons


March 25, 2013 By 
 
Cannabinoids Elicit Antidepressant-Like Behavior and Activate Serotonergic Neurons through the Medial Prefrontal Cortex.
Preclinical and clinical studies show that cannabis modulates mood and possesses antidepressant-like properties, mediated by the agonistic activity of cannabinoids on central CB1 receptors (CB1Rs). The action of CB1R agonists on the serotonin (5-HT) system, the major transmitter system involved in mood control and implicated in the mechanism of action of antidepressants, remains however poorly understood. In this study, we demonstrated that, at low doses, the CB1R agonist WIN55,212-2 [R(+)-[2,3-dihydro-5-methyl-3-[(morpholinyl)]pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl) methanone mesylate] exerts potent antidepressant-like properties in the rat forced-swim test (FST). This effect is CB1R dependent because it was blocked by the CB1R antagonist rimonabant and is 5-HT mediated because it was abolished by pretreatment with the 5-HT-depleting agent parachlorophenylalanine. Then, using in vivo electrophysiology, we showed that low doses of WIN55,212-2 dose dependently enhanced dorsal raphe nucleus 5-HT neuronal activity through a CB1R-dependent mechanism. Conversely, high doses of WIN55,212-2 were ineffective in the FST and decreased 5-HT neuronal activity through a CB1R-independent mechanism. The CB1R agonist-induced enhancement of 5-HT neuronal activity was abolished by total or medial prefrontocortical, but not by lateral prefrontocortical, transection. Furthermore, 5-HT neuronal activity was enhanced by the local microinjection of WIN55,212-2 into the ventromedial prefrontal cortex (mPFCv) but not by the local microinjection of WIN55,212-2 into the lateral prefrontal cortex. Similarly, the microinjection of WIN55,212-2 into the mPFCv produced a CB1R-dependent antidepressant-like effect in the FST. These results demonstrate that CB1R agonists possess antidepressant-like properties and modulate 5-HT neuronal activity via the mPFCv.
1Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montréal, Quebec, Canada H3A 1A1, and 2Department of Psychiatry, Centre de Recherche Fernand Seguin, Hôpital L.H. Lafontaine, Université de Montréal, Quebec, Canada H1N 3V2
Correspondence should be addressed to Dr. Gabriella Gobbi, Neurobiological Psychiatry Unit, Department of Psychiatry, Research and Training Building, McGill University, 1033 Pine Avenue West, Montréal, Quebec, Canada H3A 1A1. Email: gabriella.gobbi@mcgill.ca

Marijuana May Spur New Brain Cells

March 25, 2013 By 
Washington, D.C. — Scientists said October 13, 2005 that marijuana appears to promote the development of new brain cells in rats and have anti-anxiety and anti-depressant effects, a finding that could have an impact on the national debate over medical uses of the drug.
Other illegal and legal drugs, including opiates, alcohol, nicotine and co*aine, have been shown to suppress the formation of new brain cells when used chronically, but marijuana’s effect on that process was uncertain.
Now, a team led by Xia Zhang of the department of psychiatry at the University of Saskatchewan in Saskatoon may have found evidence the drug spurs new brain cells to form in a region of the brain called the hippocampus, and this in turn reduces anxiety and depression.
Marijuana appears “to be the only illicit drug whose capacity to produce increased … neurons is positively correlated with its (anti-anxiety) and anti-depressant-like effects,” Zhang and colleagues wrote in the November issue of the Journal of Clinical Investigation. The paper was posted online Thursday.
In the study, rats were given injections of HU210 — a synthesized version of a cannabinoid chemical found in marijuana — twice per day for 10 days.
Zhang told United Press International this would be “a high dose” of smoked marijuana, but he added he is not certain how many equivalent joints it would take or whether patients now using the drug typically would be getting this much HU210.
Although HU210 was injected, Zhang said there would be no difference if it was obtained by smoking marijuana.
The rats showed evidence of new neurons in the hippocampus dentate gyrus, a region of the brain that plays a role in developing memories.
Zhang’s team suspected the new brain cells also might be associated with a reduction in anxiety and depression, because previous studies had indicated medications used to treat anxiety and depression achieve their effect this way.
To find out, they treated rats with HU210 for 10 days and then tested them one month later. When placed in a new environment, the rats were quicker to eat their food than rats that did not receive the compound, which suggested there was a reduction in anxiety behaviors.
Another group of rats treated with HU210 showed a reduction in the duration of immobility in a forced swimming test, which is an indication the compound had an anti-depressant effect.
Asked how he thought the findings might impact the debate over using marijuana to treat medical conditions, Zhang said, “Our results indicate cannabinoids could be used for the treatment of anxiety and depression.”
He added that his view is “marijuana should be used as alcohol or nicotine,” noting “it has been used for treating various diseases for years in other countries.”
Last June the U.S. Supreme Court voted 6-3 that the federal ban on marijuana supersedes the laws of certain states that allow the substance to be used for medicinal purposes, such as the treatment of pain, nausea in cancer patients and glaucoma. Eleven states have passed laws legalizing marijuana use by patients with a doctor’s approval, including California, Alaska, Colorado, Hawaii, Maine, Montana, Nevada, Oregon, Vermont and Washington.
The Bush administration, through the Department of Justice’s Drug Enforcement Agency, began conducting raids in California in 2001 on patients using marijuana. Two of those arrested by the DEA — Angel Raich, who suffers from brain cancer, and Diane Monson, who used the drug to help alleviate chronic back pain — sued Attorney General John Ashcroft, requesting a court order to be allowed to grow and smoke marijuana, which led to the Supreme Court decision.
Paul Armentano, senior policy analyst with the National Organization for the Reform of Marijuana Laws, told UPI he thought the findings “would have a positive impact on moving forward this debate, because it is giving … a scientific explanation that further supports long-observed anecdotal evidence, and further lends itself to the notion that marijuana, unlike so many other prescription drugs and controlled substances, appears to have incredibly low toxicity and as a result lacks potential harm to the brain that many of these drugs have.”
The DEA Web site, however, contends that “marijuana is a dangerous, addictive drug that poses significant health threats to users,” including cancer and impaired mental functioning.
Armentano said this is a distortion of what scientific studies actually show. Studies in animals indicate marijuana actually may protect against many forms of cancer, rather than cause the disease, he said. In addition, studies in marijuana smokers have found little evidence of cognitive deficits, and even when they do, the defects disappear if the person stops smoking for 30 days.

A Cooling Effect From Cannabis?


March 25, 2013 By 
By Tod Mikuriya, MD
It has been observed by my office staff and confirmed anecdotally by colleagues that people seeking physician approval to medicate with cannabis usually register body temperatures markedly below 98.6.
Hypothermia in the mouse is one of the “classic tetrad” of symptoms indicating activation of the cannabinoid system. The genesis of hypothermia requires further study. The Indian Hemp Drugs Commission observed that one of the reputed benefits was to help laborers tolerate the heat. Cannabis was described as used to cool the passions —in contrast with alcohol, which heated them.
A slower metabolic rate, over time, might have implications for longevity.
Clinically, cannabis appears to actually lower temperature and a couple of patients have described a sense of cold with transient shivering. The question could be answered readily by comparing temperatures of persons who have THC metabolites in their urine and people who don’t. If there turns out to be a significantly lower temperature in the cannabis-using population, one might posit a slower metabolic rate which, over time, might have implications for longevity. Temperature has a significant effect on metabolic rate. We have to understand the mechanism of hypothermogenesis.
If there is a hypothermia, what influence is there on the HPA (Hypothalamus Pituitary Adrenal networks) and all of the interactions affecting levels of circulating cortisol and epinephrine, etc.? With management of diabetes, cannabis decreases blood sugar by diminishing gluconeogenesis, which plays out in decreased insulin requirement and improved stability.
This hypothermogenic effect appears to be dose-related and could contribute to a neuroprotective effect after trauma. The optimum delivery method will require study. Hopefully, we will see a vaporizer on ambulances for treatment of head injury and seizures, and at the bedside of pre- and post-neurosurgery patients.
In addition to external cooling, cannabis quiets the irritable CNS. A combination of inhaled and oral cannabis would be appropriate for acute CNS trauma from internal or external etiology. I predict this will become accepted and mainstream in the future.
Raphael Mechoulam’s lab published a paper in 2003 showing that hypothermia appears to be an important factor as to why the synthetic THC analog HU-210 was protective in an animal model of stroke. [Leker, R.R., Gai, N., Mechoulam, R. and Ovadia, H. (2003) Drug-induced hypothermia reduces ischemic damage: effects of the cannabinoid HU-210. Stroke 34, 2000-2006]… If a patient presents to an ER with a stroke, the first thing they will do is put the patient’s head in a cooler and pump them full of antioxidants (vitamin E).

The Myth of Marijuana's Gateway Effect

by John P. Morgan, M.D. and Lynn Zimmer, Ph.D.

The Partnership for a Drug-Free America, in cooperation with the National Institute on Drug Abuse (NIDA) and the White House Office of Drug Control Policy, recently announced a new anti-drug campaign that specifically targets marijuana. Instead of featuring horror tales of marijuana-induced insanity, violence and birth detects, this campaign is built upon the premise that reducing marijuana use is a practical strategy for reducing the use of more dangerous drugs.

The primary basis for this "gateway hypothesis" is a recent report by the center on Addiction and Substance Abuse (CASA), claiming that marijuana users are 85 times more likely than non-marijuana users to try cocaine. This figure, using data from NIDA's 1991 National Household Survey on Drug Abuse, is close to being meaningless. It was calculated by dividing the proportion of marijuana users who have ever used cocaine (17%) by the proportion of cocaine users who have never used marijuana (.2%). The high risk-factor obtained is a product not of the fact that so many marijuana users use cocaine but that so many cocaine users used marijuana previously
.
It is hardly a revelation that people who use one of the least popular drugs are likely to use the more popular ones -- not only marijuana, but also alcohol and tobacco cigarettes. The obvious statistic not publicized by CASA is that most marijuana users -- 83 percent -- never use cocaine. Indeed, for the nearly 70 million Americans who have tried marijuana, it is clearly a "terminus" rather than a "gateway" drug.
During the last few years, after a decade of decline, there has been a slight increase in marijuana use, particularly among youth. In 1994, 38 percent of high school seniors reported having ever tried the drug, compared to about 35 percent in 1993 and 33 percent in 1992. This increase does not constitute a crisis. No one knows whether marijuana use-rates will continue to rise. But even if they do, it will not necessarily lead to increased use of cocaine.

Since the 1970s, when NIDA first began gathering data, rates of marijuana and cocaine use have displayed divergent patterns. Marijuana prevalence increased throughout the 1970s, peaking in 1979, when about 60 percent of high school seniors reported having used it at least once. During the 1980s, cocaine use increased while marijuana use was declining. Since 1991, when data for the CASA analysis were gathered, marijuana use-rates have increased while cocaine use-rates have remained fairly steady.
The over-changing nature of the statistical relationship between use-rate for marijuana and cocaine indicates the absence of a causal link between the use of these two drugs. Therefore, even if the proposed Partnership campaign were to be effective in reducing marijuana use it would not guarantee a proportional reduction in the number of people who use cocaine. To the extent anti-drug campaigns are effective, they seem to be most effective in deterring those people who would have been fairly low-level users. There is no reason to believe that anti-marijuana messages of any sort would deter many of those marijuana users -- currently 17 percent of the total -- who also develop an interest in cocaine.

Nor is there reason to believe that the Partnership's new campaign will actually reduce the overall number of marijuana users. For a decade now, American youth have been subjected to an unparalleled assault of anti-drug messages. They have seen hundreds of Partnership advertisements, on television and in the print media. They have been urged to "just say no" by rock stars, sports heroes, presidents and first-ladies. They have been exposed to anti-drug educational programs in the schools. Yet this is the same generation of young people that recently began increasing its use of marijuana. It seems unlikely that many of them will be deterred by hyperbolic claims of marijuana's gateway effect, particularly when it contradicts the reality of drug use they see around them.
If the creators of American drug policy are truly interested in reducing the risk of marijuana users using other drugs, they should take a closer look at Holland, where drug policy since the 1970s has been guided by a commitment to diminishing any potential gateway effect. Wanting to keep young marijuana users away from cocaine and other "hard drugs," the Dutch decided to separate the retail markets by allowing anyone 18 years of age or older to purchase marijuana openly in government-controlled "coffee shops" which strictly prohibit the use and sale of other drugs.

Despite easy availability, marijuana prevalence among 12 to 18 year olds in Holland is only 13.6 percent -- well below the 38 percent use-rate for American high school seniors. More Dutch teenagers use marijuana now than in the past; indeed, lifetime prevalence increased nearly three-fold between 1984 and 1992, from
4.8 to 13.6 percent. However, Dutch officials consider their policy a success because the increase in marijuana use has not been accompanied by an increase in the use of other drugs. For the last decade, the rate of cocaine use among Dutch youth has remained stable, with about .3 percent of 12-18 year olds reporting having used it in the past month.

In the United States, the claim that marijuana acts as a gateway to the use of other drugs serves mainly as a rhetorical tool for frightening Americans into believing that winning the war against heroin and cocaine requires waging & battle against the casual use of marijuana. Not only is the claim intellectually indefensible, but the battle is wasteful of resources and fated to failure.

Received by Iowa NORML from the National Organization for the Reform of Marijuana Laws (NORML), 1001 Connecticut Avenue, N.W., Suite 1010, Washington, D.C. 20036, on Tuesday, February 7, 1995. For more information, call Allen St. Pierre, NORML Assistant Director, at (202) 483-5500, or e-mail NORML at natlnorml@aol.com 

Uruguayan President Wants to Legalize Marijuana

Uruguayan President Wants to Legalize Marijuana, Even If He's Never Tried It

PHOTO: Uruguayan President Jose Mujica and his wife Lucia Topolansky
According to ABC news, Earlier this week, Uruguayan President José Mújica, a progressive politician who is pushing a law to legalize marijuana consumption in Uruguay, confessed that he has never smoked weed.
"I have never tried it in my life and I don't know what it is," Mújica told Radio Carve, a local radio station. He added that he's aware "a lot of young people have tried it."
Mújica's somewhat surprising admission came shortly before he met with José Miguel Insulza, Secretary General of the Organization of American States (OAS), to discuss a recent report on drug consumption in the Americas. The report favored drug decriminalization of marijuana, an initiative that Uruguayan legislators have been discussing for nearly a year.
"We don't have any objections against this process moving forward," Insulza said in reference to a marijuana legalization bill in Uruguay. "We don't support it openly because we don't have a mandate from [OAS] member countries, but that is the road that is being followed. The marijuana debate is now open and it's going to lead to changes."
Mújica, a former guerrilla fighter known for his humility and kindness, and the Broad Front, a coalition of left-wing parties of which Mújica is a member, are supporting this bill, which would allow Uruguayans over the age of 18 to buy up to 40 grams of weed per month from state-sanctioned distributors.
The legislation was first introduced in 2012 in order to fight drug consumption and drug trafficking. Last December, the government had the necessary votes to pass the bill, but President Mújica asked parliament not to vote in the legislation after a poll revealed that most Uruguayans did not favor the initiative. ("Don't vote on a law because you have majority in parliament," Mújica said back then. "Support has to come from the streets.")
The president then charged the bill's leading supporters with convincing Uruguayans of the importance of marijuana legalization. Since then, the vote has been delayed and legislators both in favor and against the initiative have tried to court public opinion through media appearances and op-eds in the nation's most important newspapers.
The vote is now set for July 31, 2013.
According to Uruguayan newspaper El Observador, the Broad Front now has 49 of the 50 required votes for the bill to clear the Lower Chamber. The coalition is still striving to convince Darío Pérez, who has met with Mújica to discuss the matter. Other options include José Carlos Cardoso, a legislator from an opposition party who agrees with the policy but who is still unwilling to go against his political organization.
Insulza's visit, largely seen as a show of support for Mújica's initiative, could well help secure that 50th vote. On Monday, the OAS Secretary General said that legalizing marijuana is a strategy that is worth trying. He also made point of highlighting that Uruguay is the first country where he is presenting the OAS report "The Drug Problem in the Americas."
"What better place to start than here, where there is already a debate," Insulza said.

Majority of D.C. Council signs on to bill to decriminalize pot

By Tim Craig,July 10, 2013


A majority of D.C. Council members on Wednesday signed on to a bill to decriminalize possession of up to an ounce of marijuana, giving the proposal considerable momentum as the body prepares to consider the matter this fall.
Council members Tommy Wells (D-Ward 6) and Marion Barry (D-Ward 8) drafted the bill, which would make possession of the drug subject to a $100 civil fine.
Six other council members signed on as co-sponsors — Democrats Anita Bonds (At large), Jim Graham (Ward 1), Jack Evans (Ward 2), Kenyan McDuffie (Ward 5), Mary M. Cheh (Ward 3) as well as Independent David Grosso (at large).

“Lets get this done and stop arresting, mostly black men, for small amounts of marijuana,” Barry said.



Wells, the chairman of the Public Safety and Judiciary Committee, said the strong support leaves him optimistic the proposal can be put up for a formal vote before Christmas.
But in a statement, Police Chief Cathy Lanier urged a “robust discussion,” calling it a “significant issue.” Lanier said she has concerns about the risks marijuana poses for children, as well as potential conflict with federal law.
“It is important for the community to recognize that some of the information being used as an argument for decriminalization is flawed,” said Lanier, referring to a report by the American Civil Liberties Union released last month that showed the District outranked the 50 states in per-capita marijuana arrests.
The study also found that African Americans in the District were eight times more likely than whites to be arrested for marijuana possession.
Council member Yvette Alexander (D-Ward 7) also said she will not be supporting the proposal She questioned Barry and Wells’s argument that decriminalization will help more District residents land jobs.
“When you apply for a job, and there is a drug test, and you come up positive, you still can’t get the job,” Alexander said. “So why would we make it one step closer for people to smoke marijuana?”

Medical Marijuana Activists Appeal to US Supreme Court


David Downs —  Tue, Jul 16, 2013 at 9:21 AM

Medical cannabis advocacy group Americans for Safe Access (ASA) will ask the US Supreme Court to review the United States' classification of marijuana as more dangerous than cocaine, meth, or Oxycodone. Oakland-based ASA said Monday that they had filed a petition with the US Supreme Court to appeal a January Circuit Court decision which maintains cannabis' prohibition as one of the world's most dangerous drugs.
The Drug Enforcement Administration classifies pot as a "schedule 1" narcotic with a high potential for abuse and no medical use. ASA took the DEA to court arguing the classification is wrong. Marijuana is one of the least addictive drugs on the planet and it is impossible to overdose on it. Conversely, about 30,000 Americans die every year from unintentional overdoses of Vicodin, Oxycodone, and other FDA-approved prescription drugs that are schedule 2 or lower.
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In January, the circuit court found that there is not enough research on medical uses of pot and denied ASA's petition.
ASA argues in its SCOTUS appeal that the District of Columbia Circuit Court used an unreasonable and unprecedented standard in denying ASA's petition for a re-schedule. More than two hundred peer-reviewed studies attest to cannabis' medical efficacy, ASA states. Three out of four doctors polled by the New England Journal of Medicine in May also recommended cannabis for a hypothetical breast cancer patient.
But no major drug company has tried to bring cannabis to market, the circuit court argued. ASA contends that this opinion conflicts with another circuit court ruling made in 1987.
In that ruling, the court said that FDA marketing approval of a drug does not make it a medicine. ASA also notes that federal law all but bans research on medical uses of cannabis, creating a ludicrous, unscientific Catch-22.
"The court has unreasonably raised the bar for what qualifies as an 'adequate and well-controlled' study thereby continuing the government's game of 'Gotcha'," stated Kris Hermes for ASA.
ASA has been working on the reclassification case since 2002.